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- Title
A smoking cessation trial with lobeline sulfate: a pilot study.
- Authors
Glover ED; Leischow SJ; Rennard SI; Glover PN; Daughton D; Quiring JN; Schneider FH; Mione PJ
- Abstract
Objective: To evaluate a sublingual formulation of lobeline sulfate for smoking cessation. Methods: Random assignment of 180 healthy smokers to treatment (n=90) or placebo (n=90). Treatment was self-administering a 7.5 mg lobeline sulfate sublingual or placebo tablet 9 times per day for 6 weeks. Results: No difference in cessation efficacy between placebo and active treatment. Among highly dependent smokers who completed the trial, there was a trend for higher cessation rates in the active group. Conclusion: This pilot study failed to demonstrate smoking-cessation efficacy. However, data suggest continued studies to evaluate lobeline sulfate for smoking cessation.
- Publication
American Journal of Health Behavior, 1998, Vol 22, Issue 1, p62
- ISSN
1087-3244
- Publication type
Academic Journal