We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
6-Bromo-2'-(2-chlorobenzylidene)nicotinohydrazide and 6-Bromo-2'-(3-bromo-5-chloro-2-hydroxybenzylidene) nicotinohydrazide Methanol Solvate: Synthesis, Characterization, Crystal Structures and Antimicrobial Activities.
- Authors
Hai-Yun Zhu
- Abstract
Two newly synthesized nicotinohydrazones, 6-bromo-2'-(2-chlorobenzylidene)nicotinohydrazide (1) and 6-bromo-2'- (3-bromo-5-chloro-2-hydroxybenzylidene)nicotinohydrazide methanol solvate (2), have been obtained and structurally characterized by spectroscopic method and single crystal X-ray determination. The molecules in both compounds are in E configuration regarding to the azomethine groups. The molecules of compound 1 are linked via hydrogen bonds of N-H⋯O, generating one dimensional chains running along the c-axis direction. The hydrazone molecules of compound 2 are linked by methanol molecules via hydrogen bonds of N-H⋯O and O-H⋯N, generating dimers. The in vitro antimicrobial activities of these compounds indicate that they are interesting antibacterial agents.
- Publication
Acta Chimica Slovenica, 2021, Vol 68, Issue 1, p65
- ISSN
1318-0207
- Publication type
Academic Journal
- DOI
10.17344/acsi.2020.6138