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- Title
SÍNTESE DE NOVOS DERIVADOS DE BIOCIDAS N-ALQUILADOS DE QUINAZOLINA-4(3H)-ONA USANDO ATIVAÇÃO DE MICROONDAS.
- Authors
El-Badry, Yaser A.; Abdou, Safaa N.
- Abstract
Microwave-assisted construction of 2-propylquinazolinone1 has been achieved, followed by its subsequent utilities in constructing an attractive series of 2,3-disubstituted functional quinazolinones 2-10. The use of microwave irradiation in performing A/-alkylation for the titled quinazolinone 1 was applied as a simple, efficient and eco-friendly green technique. Furthermore, the in vitro antimicrobial screening of the obtained compounds 3-10 has been investigated against four bacterial strains and two fungal strains. The structure of the synthesized molecules was affirmed using analytical and spectral tools.
- Publication
Periódico Tchê Química, 2018, Vol 15, Issue 30, p463
- ISSN
1806-0374
- Publication type
Academic Journal
- DOI
10.52571/ptq.v15.n30.2018.466_periodico30_pgs_463_472.pdf