We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Lactobacilli and Bifidobacterium as anti-atherosclerotic agents.
- Authors
Abdi, Milad; Gouvarchin Ghaleh, Hadi Esmaeili; Ranjbar, Reza
- Abstract
Atherosclerosis is the thickening or hardening of the arteries which is caused by a buildup of atheromatous plaque in the inner lining of an artery. Hypercholesterolemia, inflammation, oxidative stress, and trimethylamine N-oxide (TMAO) are important risk factors for atherosclerosis. Therefore, this study aimed to review the anti-atherosclerotic effects of Lactobacilli and Bifidobacterium via improving lipid profile and reducing the effects of oxidative stress, inflammation, and TMAO. To prepare the present review, several databases such as Scopus, PubMed, and Google Scholar were searched, and relevant articles from 1990 until 2022 were selected and reviewed. The present review showed that Lactobacilli and Bifidobacterium reduce the risk of atherosclerosis in both in vitro and in vivo studies by breaking down or altering cholesterol metabolism with the help of their by-products and by reducing inflammation and oxidative stress and TMAO. Consumption of Lactobacilli and Bifidobacterium can be useful in prevention of atherosclerosis.
- Publication
Iranian Journal of Basic Medical Sciences, 2022, Vol 25, Issue 8, p934
- ISSN
2008-3866
- Publication type
Academic Journal
- DOI
10.22038/IJBMS.2022.63860.14073