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- Title
Influence of Quercetin on Proliferation and Invasive Ability of High-metabasis Hepatoma Cells.
- Authors
LIU Feng; LI Gang; HU Ming-dao; WANG Zhi-ping; Yong-jun, A.
- Abstract
Objective To explore the influence of quercetin on the proliferation and invasive ability of high-metabasis hepatoma cells. Methods Human high-meabasis HCC cell line(HCCLM6) was used in this study. The inverted phase contrast microscope was used to observe the influence of quercetin on the morphosis of HCCLM6 cells. MTT method was used to detect the effect of quercetin on the proliferation of hepatoma cells. Transwell chamber assay was used to determine the influence of quercetin on the invasive ability of HCCLM6 cells. Results By the inverted microscope, low cell density and the increase of suspension cells were observed in quercetin-treated group. Compared with control group, cell survival rate decreased more significantly in quercetin-treated group. Quercetin inhibited the invasion of HCCLM6 cells in transwell chamber. Conclusion Quercetin can inhibit the proliferation and invasive ability of HCCLM6 cells.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2014, Vol 35, Issue 5, p29
- ISSN
2095-610X
- Publication type
Academic Journal