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- Title
Attempted side-chain bromination of o/p-hydroxyacetophenones using various brominating reagents: eco-friendly and convenient methods for nuclear bromination.
- Authors
Arora, Loveena; Kapoor, Jitander K.
- Abstract
Reaction of o/p-hydroxyacetophenones with NH4Br-(NH4)2S2O8 under aqueous grinding conditions, NH4Br-oxone/methanol and Zn-Br2/H2O leads to nuclear bromination with the formation of mono and dibromo derivatives depending upon the amount of the reagents used. The results obtained from our investigations are in sharp contrast to the results of the reported work on side-chain bromination of such ketones. The study offers eco-friendly and convenient methods for nuclear bromination of o/p-hydroxyacetophenones.
- Publication
Chemistry & Biology Interface, 2017, Vol 7, Issue 1, p57
- ISSN
2249-4820
- Publication type
Academic Journal